Ramis acknowledged that the film was his most memorable work but took pride in its longevity.
“People love Ghostbusters in a really big way,” he said in 2009. “Parents loved it for their kids. Teachers loved it.
“We got mail from teachers who said they loved that kids were playing Ghostbusters at recess because it was a non-violent game that didn’t divide the kids into good guys and bad guys and the games were very co-operative. It’s really had some power.”
He died of autoimmune inflammatory vasculitis, a rare disease that involves swelling of the blood vessels, his agent told the BBC.